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Inactivation of the Bacterial RNA Polymerase Due to Acquisition of Secondary Structure by the ω Subunit

The widely conserved ω subunit encoded by rpoZ is the smallest subunit of Escherichia coli RNA polymerase (RNAP) but is dispensable for bacterial growth. Function of ω is known to be substituted by GroEL in ω-null strain, which thus does not exhibit a discernable phenotype. In this work, we report i...

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Main Authors: Sarkar, Paramita, Sardesai, Abhijit A., Murakami, Katsuhiko S., Chatterji, Dipankar
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757172/
https://ncbi.nlm.nih.gov/pubmed/23843456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468520
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