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SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas
Synovial sarcoma is a deadly malignancy with limited sensitivity to traditional cytotoxic chemotherapy. SS18-SSX fusion oncogene expression characterizes human synovial sarcomas and drives oncogenesis in a mouse model. Elevated expression of BCL2 is considered a consistent feature of the synovial sa...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3756901/ https://ncbi.nlm.nih.gov/pubmed/22797074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.247 |
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