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Discovery and activity profiling of thailandepsins A through F, potent histone deacetylase inhibitors, from Burkholderia thailandensis E264

Three new bicyclic depsipeptides, which are related to the previously reported thailandepsins A (1), B (2) and C (3), were discovered from the culture broth of Burkholderia thailandensis E264 when supplemented with amino acid precursors, and were subsequently named as thailandepsins D (4), E (5) and...

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Bibliographic Details
Main Authors: Wang, Cheng, Flemming, Creston J., Cheng, Yi-Qiang
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755959/
https://ncbi.nlm.nih.gov/pubmed/23997923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2MD20024D
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