Anti-GD(2) with an FC point mutation reduces complement fixation and decreases antibody-induced allodynia

Monoclonal antibodies against GD(2) ganglioside, such as ch14.18, the human–mouse chimeric antibody, have been shown to be effective for the treatment of neuroblastoma. However, treatment is associated with generalized, relatively opiate-resistant pain. We investigated if a point mutation in ch14.18...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Sorkin, Linda S., Otto, Mario, Baldwin, William M., Vail, Emily, Gillies, Stephen D., Handgretinger, Rupert, Barfield, Raymond C., Yu, Hui Ming, Yu, Alice L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755890/
https://ncbi.nlm.nih.gov/pubmed/20171010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.01.024
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller