Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass

Aging reduces the number of mesenchymal stem cells (MSCs) in the bone marrow which leads to impairment of osteogenesis. However, if MSCs could be directed toward osteogenic differentiation, they could be a viable therapeutic option for bone regeneration. We have developed a method to direct the MSCs...

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Detalhes bibliográficos
Main Authors: Guan, Min, Yao, Wei, Liu, Ruiwu, Lam, Kit S., Nolta, Jan, Jia, Junjing, Panganiban, Brian, Meng, Liping, Zhou, Ping, Shahnazari, Mohammad, Ritchie, Robert O., Lane, Nancy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755884/
https://ncbi.nlm.nih.gov/pubmed/22306732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2665
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