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Development of an intracellularly acting inhibitory peptide selective for PKN

PKNs form a subfamily of the AGC serine/threonine protein kinases, and have a catalytic domain homologous with that of PKC (protein kinase C) in the C-terminal region and three characteristic ACC (antiparallel coiled-coil) domain repeats in the N-terminal region. The preferred peptide phosphorylatio...

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Autors principals: Shiga, Kazuhiro, Takayama, Kentaro, Futaki, Shiroh, Hutti, Jessica E., Cantley, Lewis C., Ueki, Katsuko, Ono, Yoshitaka, Mukai, Hideyuki
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755880/
https://ncbi.nlm.nih.gov/pubmed/19857203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090380
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