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DNAzyme-Based Probes for Telomerase Study in Early-Stage Cancer Detection

Human telomerase is a polymerase enzyme that adds tandem repeats of DNA (TTAGGG) in the telomere regions. Since telomerase can be detected in immortalized, but not normal, somatic cells, it has been considered a selective target for cancer chemotherapy. In this paper, we describe a DNAzyme-based pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Hui, Donovan, Michael J., Meng, Ling, Zhao, Zilong, Kim, Youngmi, Ye, Mao, Tan, Weihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755732/
https://ncbi.nlm.nih.gov/pubmed/23426940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201204440
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