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Novel Deletion Mutation Identified in a Patient with Late-Onset Combined Methylmalonic Acidemia and Homocystinuria, cblC Type

Combined methylmalonic aciduria and homocystinuria, cblC type (MMACHC), is the most common inborn error of cellular vitamin B(12) metabolism and is caused by mutations in the MMACHC gene. This metabolic disease results in impaired intracellular synthesis of adenosylcobalamin and methylcobalamin, coe...

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Detalhes bibliográficos
Main Authors: Backe, Paul Hoff, Ytre-Arne, Mari, Røhr, Åsmund Kjendseth, Brodtkorb, Else, Fowler, Brian, Rootwelt, Helge, Bjørås, Magnar, Mørkrid, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755550/
https://ncbi.nlm.nih.gov/pubmed/23580368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2013_225
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