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Complete TCRα gene locus control region activity in T cells derived in vitro from embryonic stem cells

Locus Control Regions (LCR) are cis-acting gene regulatory elements with the unique, integration site-independent ability to transfer the characteristics of their locus-of-origin’s gene expression pattern to a linked transgene in mice. LCR activities have been discovered in numerous T cell lineage e...

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Main Authors: Lahiji, Armin, Kučerová-Levisohn, Martina, Lovett, Jordana, Holmes, Roxanne, Zúñiga-Pflücker, Juan Carlos, Ortiz, Benjamin D.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755507/
https://ncbi.nlm.nih.gov/pubmed/23720809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300521
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