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STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection()

IL-4 contributes to immunopathology induced in mice by primary respiratory syncytial virus (RSV) infection. However, the cellular source of IL-4 in RSV infection is unknown. We identified CD3(−)CD49b(+) cells as the predominant source of IL-4 in the lungs of RSV-infected BALB/c mice. We ruled out T...

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Autors principals: Moore, Martin L., Newcomb, Dawn C., Parekh, Vrajesh V., Van Kaer, Luc, Collins, Robert D., Zhou, Weisong, Goleniewska, Kasia, Chi, Michael H., Mitchell, Daphne, Boyce, Joshua A., Durbin, Joan E., Sturkie, Carla, Peebles, R. Stokes
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755459/
https://ncbi.nlm.nih.gov/pubmed/19587017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803167
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