STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection()

IL-4 contributes to immunopathology induced in mice by primary respiratory syncytial virus (RSV) infection. However, the cellular source of IL-4 in RSV infection is unknown. We identified CD3(−)CD49b(+) cells as the predominant source of IL-4 in the lungs of RSV-infected BALB/c mice. We ruled out T...

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Main Authors: Moore, Martin L., Newcomb, Dawn C., Parekh, Vrajesh V., Van Kaer, Luc, Collins, Robert D., Zhou, Weisong, Goleniewska, Kasia, Chi, Michael H., Mitchell, Daphne, Boyce, Joshua A., Durbin, Joan E., Sturkie, Carla, Peebles, R. Stokes
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755459/
https://ncbi.nlm.nih.gov/pubmed/19587017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803167
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