An Attenuated Cytomegalovirus Vaccine with a Deletion of a Viral Chemokine Gene Is Protective against Congenital CMV Transmission in a Guinea Pig Model

Development of a vaccine against congenital cytomegalovirus (CMV) infection is a public health priority, but CMVs encode immune evasion genes that complicate live virus vaccine design. To resolve this problem, this study employed guanosyl phosphoribosyl transferase (gpt) mutagenesis to generate a re...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Leviton, Michael P., Lacayo, Juan C., Choi, K. Yeon, Hernandez-Alvarado, Nelmary, Wey, Andrew, Schleiss, Mark R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755440/
https://ncbi.nlm.nih.gov/pubmed/24000289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/906948
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares