Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

A critical event in ischemia-based cell death is the opening of the mitochondrial permeability transition pore (MPTP). However, the molecular identity of the components of the MPTP remains unknown. Here, we determined that the Bcl-2 family members Bax and Bak, which are central regulators of apoptot...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Karch, Jason, Kwong, Jennifer Q, Burr, Adam R, Sargent, Michelle A, Elrod, John W, Peixoto, Pablo M, Martinez-Caballero, Sonia, Osinska, Hanna, Cheng, Emily H-Y, Robbins, Jeffrey, Kinnally, Kathleen W, Molkentin, Jeffery D
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755340/
https://ncbi.nlm.nih.gov/pubmed/23991283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00772
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados