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T-cell immunosenescence: lessons learned from mouse models of aging

It is well established that increasing age is associated with a decreased capacity of the immune system to mediate effective immune responses to vaccination and invading pathogens. Because of the inherent limitations of conducting experiments in humans, much of what we have learned is owed to the ut...

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Detalhes bibliográficos
Main Authors: Maue, Alexander C., Yager, Eric J., Swain, Susan L., Woodland, David L., Blackman, Marcia A., Haynes, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755270/
https://ncbi.nlm.nih.gov/pubmed/19541537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2009.04.007
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