DNA repair genes are selectively mutated in diffuse large B cell lymphomas

DNA repair mechanisms are fundamental for B cell development, which relies on the somatic diversification of the immunoglobulin genes by V(D)J recombination, somatic hypermutation, and class switch recombination. Their failure is postulated to promote genomic instability and malignant transformation...

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Main Authors: de Miranda, Noel FCC, Peng, Roujun, Georgiou, Konstantinos, Wu, Chenglin, Sörqvist, Elin Falk, Berglund, Mattias, Chen, Longyun, Gao, Zhibo, Lagerstedt, Kristina, Lisboa, Susana, Roos, Fredrik, van Wezel, Tom, Teixeira, Manuel R., Rosenquist, Richard, Sundström, Christer, Enblad, Gunilla, Nilsson, Mats, Zeng, Yixin, Kipling, David, Pan-Hammarström, Qiang
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2013
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754869/
https://ncbi.nlm.nih.gov/pubmed/23960188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122842
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