Učitavanje...
DNA repair genes are selectively mutated in diffuse large B cell lymphomas
DNA repair mechanisms are fundamental for B cell development, which relies on the somatic diversification of the immunoglobulin genes by V(D)J recombination, somatic hypermutation, and class switch recombination. Their failure is postulated to promote genomic instability and malignant transformation...
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Glavni autori: | , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The Rockefeller University Press
2013
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754869/ https://ncbi.nlm.nih.gov/pubmed/23960188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122842 |
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