DNA repair genes are selectively mutated in diffuse large B cell lymphomas

DNA repair mechanisms are fundamental for B cell development, which relies on the somatic diversification of the immunoglobulin genes by V(D)J recombination, somatic hypermutation, and class switch recombination. Their failure is postulated to promote genomic instability and malignant transformation...

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Bibliografski detalji
Glavni autori: de Miranda, Noel FCC, Peng, Roujun, Georgiou, Konstantinos, Wu, Chenglin, Sörqvist, Elin Falk, Berglund, Mattias, Chen, Longyun, Gao, Zhibo, Lagerstedt, Kristina, Lisboa, Susana, Roos, Fredrik, van Wezel, Tom, Teixeira, Manuel R., Rosenquist, Richard, Sundström, Christer, Enblad, Gunilla, Nilsson, Mats, Zeng, Yixin, Kipling, David, Pan-Hammarström, Qiang
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754869/
https://ncbi.nlm.nih.gov/pubmed/23960188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122842
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