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A role for gut-associated lymphoid tissue in shaping the human B cell repertoire

We have tracked the fate of immature human B cells at a critical stage in their development when the mature B cell repertoire is shaped. We show that a major subset of bone marrow emigrant immature human B cells, the transitional 2 (T2) B cells, homes to gut-associated lymphoid tissue (GALT) and tha...

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Detalhes bibliográficos
Main Authors: Vossenkämper, Anna, Blair, Paul A., Safinia, Niloufar, Fraser, Louise D., Das, Lisa, Sanders, Theodore J., Stagg, Andrew J., Sanderson, Jeremy D., Taylor, Kirstin, Chang, Fuju, Choong, Lee M., D’Cruz, David P., MacDonald, Thomas T., Lombardi, Giovanna, Spencer, Jo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754866/
https://ncbi.nlm.nih.gov/pubmed/23940259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122465
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