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Estrogen causes ATBF1 protein degradation through the estrogen-responsive E3 ubiquitin ligase EFP
We previously revealed that tumor suppressor ATBF1 formed an autoregulatory feedback loop with estrogen-ERα signaling to regulate estrogen-dependent cell proliferation in breast cancer cells. In this loop, ATBF1 inhibits the function of estrogen-ERα signaling while ATBF1 protein levels are fine-tune...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754848/ https://ncbi.nlm.nih.gov/pubmed/22452784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111890 |
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