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Estrogen causes degradation of KLF5 by inducing the E3 ubiquitin ligase EFP in ER-positive breast cancer cells
Krüppel-like factor 5 (KLF5) is a multifunctional transcription factor involved in cell proliferation, differentiation and carcinogenesis. In addition to frequent inactivation in different types of human cancers including breast cancer, KLF5 has been identified as an essential co-factor for the TGF-...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733548/ https://ncbi.nlm.nih.gov/pubmed/21542805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101388 |
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