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Pilus Gene Pool Variation and the Virulence of Corynebacterium diphtheriae Clinical Isolates during Infection of a Nematode

Toxigenic Corynebacterium diphtheriae strains cause diphtheria in humans. The toxigenic C. diphtheriae isolate NCTC13129 produces three distinct heterotrimeric pili that contain SpaA, SpaD, and SpaH, making up the shaft structure. The SpaA pili are known to mediate bacterial adherence to pharyngeal...

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Detalhes bibliográficos
Main Authors: Broadway, Melissa M., Rogers, Elizabeth A., Chang, Chungyu, Huang, I-Hsiu, Dwivedi, Prabhat, Yildirim, Suleyman, Schmitt, Michael P., Das, Asis, Ton-That, Hung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754579/
https://ncbi.nlm.nih.gov/pubmed/23772071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00500-13
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