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A thiol-disulfide oxidoreductase of the Gram-positive pathogen Corynebacterium diphtheriae is essential for viability, pilus assembly, toxin production and virulence

The Gram-positive pathogen Corynebacterium diphtheriae exports through the Sec apparatus many extracellular proteins that include the key virulence factors diphtheria toxin and the adhesive pili. How these proteins attain their native conformations after translocation as unfolded precursors remains...

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Vydáno v:Mol Microbiol
Hlavní autoři: Reardon-Robinson, Melissa E., Osipiuk, Jerzy, Jooya, Neda, Chang, Chungyu, Joachimiak, Andrzej, Das, Asis, Ton-That, Hung
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981772/
https://ncbi.nlm.nih.gov/pubmed/26294390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13172
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