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Does Binding of Complement Factor H to the Meningococcal Vaccine Antigen, Factor H Binding Protein, Decrease Protective Serum Antibody Responses?

Factor H binding protein (fHbp) is a principal antigen in a multicomponent meningococcal vaccine recently licensed in Europe for prevention of serogroup B diseases. The protein recruits the complement downregulator, factor H (fH), to the bacterial surface, which enables the organism to resist comple...

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Detalhes bibliográficos
Main Authors: Granoff, Dan M., Ram, Sanjay, Beernink, Peter T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754512/
https://ncbi.nlm.nih.gov/pubmed/23740919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00260-13
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