Prototypical Recombinant Multi-Protease-Inhibitor-Resistant Infectious Molecular Clones of Human Immunodeficiency Virus Type 1

The many genetic manifestations of HIV-1 protease inhibitor (PI) resistance present challenges to research into the mechanisms of PI resistance and the assessment of new PIs. To address these challenges, we created a panel of recombinant multi-PI-resistant infectious molecular clones designed to rep...

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Main Authors: Varghese, Vici, Mitsuya, Yumi, Fessel, W. Jeffrey, Liu, Tommy F., Melikian, George L., Katzenstein, David A., Schiffer, Celia A., Holmes, Susan P., Shafer, Robert W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754322/
https://ncbi.nlm.nih.gov/pubmed/23796938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00614-13
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