Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells

Background. Patients with advanced hematologic malignancies remain at risk for relapse following reduced-intensity conditioning (RIC) allogeneic hematopoietic stem cell transplantation (allo-HSCT). We conducted a prospective clinical trial to test whether vaccination with whole leukemia cells early...

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Detalhes bibliográficos
Main Authors: Burkhardt, Ute E., Hainz, Ursula, Stevenson, Kristen, Goldstein, Natalie R., Pasek, Mildred, Naito, Masayasu, Wu, Di, Ho, Vincent T., Alonso, Anselmo, Hammond, Naa Norkor, Wong, Jessica, Sievers, Quinlan L., Brusic, Ana, McDonough, Sean M., Zeng, Wanyong, Perrin, Ann, Brown, Jennifer R., Canning, Christine M., Koreth, John, Cutler, Corey, Armand, Philippe, Neuberg, Donna, Lee, Jeng-Shin, Antin, Joseph H., Mulligan, Richard C., Sasada, Tetsuro, Ritz, Jerome, Soiffer, Robert J., Dranoff, Glenn, Alyea, Edwin P., Wu, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754265/
https://ncbi.nlm.nih.gov/pubmed/23912587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69098
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