Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B

Hepatitis B virus (HBV) is a major human pathogen that causes immune-mediated hepatitis. Successful immunity to HBV is age dependent: viral clearance occurs in most adults, whereas neonates and young children usually develop chronic infection. Using a mouse model of HBV infection, we sought mechanis...

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Hauptverfasser: Publicover, Jean, Gaggar, Anuj, Nishimura, Stephen, Van Horn, Christine M., Goodsell, Amanda, Muench, Marcus O., Reinhardt, R. Lee, van Rooijen, Nico, Wakil, Adil E., Peters, Marion, Cyster, Jason G., Erle, David J., Rosenthal, Philip, Cooper, Stewart, Baron, Jody L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754256/
https://ncbi.nlm.nih.gov/pubmed/23925290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68182
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