Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B

Hepatitis B virus (HBV) is a major human pathogen that causes immune-mediated hepatitis. Successful immunity to HBV is age dependent: viral clearance occurs in most adults, whereas neonates and young children usually develop chronic infection. Using a mouse model of HBV infection, we sought mechanis...

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Detalhes bibliográficos
Main Authors: Publicover, Jean, Gaggar, Anuj, Nishimura, Stephen, Van Horn, Christine M., Goodsell, Amanda, Muench, Marcus O., Reinhardt, R. Lee, van Rooijen, Nico, Wakil, Adil E., Peters, Marion, Cyster, Jason G., Erle, David J., Rosenthal, Philip, Cooper, Stewart, Baron, Jody L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754256/
https://ncbi.nlm.nih.gov/pubmed/23925290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68182
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