Fanconi anemia signaling network regulates the spindle assembly checkpoint

Fanconi anemia (FA) is a heterogenous genetic disease with a high risk of cancer. The FA proteins are essential for interphase DNA damage repair; however, it is incompletely understood why FA-deficient cells also develop gross aneuploidy, leading to cancer. Here, we systematically evaluated the role...

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Hlavní autoři: Nalepa, Grzegorz, Enzor, Rikki, Sun, Zejin, Marchal, Christophe, Park, Su-Jung, Yang, Yanzhu, Tedeschi, Laura, Kelich, Stephanie, Hanenberg, Helmut, Clapp, D. Wade
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754252/
https://ncbi.nlm.nih.gov/pubmed/23934222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67364
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