Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivity

Retinoids are structurally related derivatives of vitamin A and are required for normal vision as well as cell proliferation and differentiation. Clinically, retinoids are effective in treating many skin disorders and cancers. Application of retinoids evokes substantial irritating side effects, incl...

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Main Authors: Yin, Shijin, Luo, Jialie, Qian, Aihua, Du, Junhui, Yang, Qing, Zhou, Shentai, Yu, Weihua, Du, Guangwei, Clark, Richard B., Walters, Edgar T., Carlton, Susan M., Hu, Hongzhen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2013
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754244/
https://ncbi.nlm.nih.gov/pubmed/23925292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66413
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