Immunosuppressive Property within the Streptococcus pneumoniae Cell Wall That Inhibits Generation of T Follicular Helper, Germinal Center, and Plasma Cell Response to a Coimmunized Heterologous Protein

We previously demonstrated that intact, inactivated Streptococcus pneumoniae (unencapsulated strain R36A) inhibits IgG responses to a number of coimmunized soluble antigens (Ags). In this study, we investigated the mechanism of this inhibition and whether other extracellular bacteria exhibited simil...

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Detalhes bibliográficos
Main Authors: Saumyaa, Arjunaraja, Swadhinya, Pujanauski, Lindsey, Colino, Jesus, Torres, Raul M., Snapper, Clifford M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754212/
https://ncbi.nlm.nih.gov/pubmed/23817619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00688-13
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