Sterile-α- and Armadillo Motif-Containing Protein Inhibits the TRIF-Dependent Downregulation of Signal Regulatory Protein α To Interfere with Intracellular Bacterial Elimination in Burkholderia pseudomallei-Infected Mouse Macrophages

Burkholderia pseudomallei, the causative agent of melioidosis, evades macrophage killing by suppressing the TRIF-dependent pathway, leading to inhibition of inducible nitric oxide synthase (iNOS) expression. We previously demonstrated that virulent wild-type B. pseudomallei inhibits the TRIF-depende...

Full description

Saved in:
Bibliographic Details
Main Authors: Baral, Pankaj, Utaisincharoen, Pongsak
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754201/
https://ncbi.nlm.nih.gov/pubmed/23836818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00519-13
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items