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Involvement of Signal Regulatory Protein α, a Negative Regulator of Toll-Like Receptor Signaling, in Impairing the MyD88-Independent Pathway and Intracellular Killing of Burkholderia pseudomallei-Infected Mouse Macrophages

The facultative intracellular Gram-negative bacterium Burkholderia pseudomallei is the causative agent of melioidosis and is known for its ability to evade the Toll-like receptor (TLR)-mediated innate immune response. Previously it has been demonstrated that this bacterium was able to suppress the M...

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Détails bibliographiques
Auteurs principaux: Baral, Pankaj, Utaisincharoen, Pongsak
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497423/
https://ncbi.nlm.nih.gov/pubmed/22988019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00718-12
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