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Heterologous Viral Promoters Incorporated into the Human Cytomegalovirus Genome Are Silenced during Experimental Latency

Human cytomegalovirus (HCMV) lytic phase gene expression is repressed upon entry into myeloid lineage cells where the virus establishes latency. Lytic infection is not initiated because the tegument-delivered transactivator protein pp71 fails to enter the nucleus and inactivate the Daxx-mediated cel...

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Détails bibliographiques
Auteurs principaux: Qin, Qingsong, Penkert, Rhiannon R., Kalejta, Robert F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754107/
https://ncbi.nlm.nih.gov/pubmed/23824803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01726-13
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