An Intact Sialoadhesin (Sn/SIGLEC1/CD169) Is Not Required for Attachment/Internalization of the Porcine Reproductive and Respiratory Syndrome Virus

Surface expression of SIGLEC1, also known as sialoadhesin or CD169, is considered a primary determinant of the permissiveness of porcine alveolar macrophages for infection by porcine reproductive and respiratory syndrome virus (PRRSV). In vitro, the attachment and internalization of PRRSV are depend...

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Autores principales: Prather, Randall S., Rowland, Raymond R. R., Ewen, Catherine, Trible, Benjamin, Kerrigan, Maureen, Bawa, Bhupinder, Teson, Jennifer M., Mao, Jiude, Lee, Kiho, Samuel, Melissa S., Whitworth, Kristin M., Murphy, Clifton N., Egen, Tina, Green, Jonathan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754101/
https://ncbi.nlm.nih.gov/pubmed/23785195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00177-13
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