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An Intact Sialoadhesin (Sn/SIGLEC1/CD169) Is Not Required for Attachment/Internalization of the Porcine Reproductive and Respiratory Syndrome Virus

Surface expression of SIGLEC1, also known as sialoadhesin or CD169, is considered a primary determinant of the permissiveness of porcine alveolar macrophages for infection by porcine reproductive and respiratory syndrome virus (PRRSV). In vitro, the attachment and internalization of PRRSV are depend...

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Autors principals: Prather, Randall S., Rowland, Raymond R. R., Ewen, Catherine, Trible, Benjamin, Kerrigan, Maureen, Bawa, Bhupinder, Teson, Jennifer M., Mao, Jiude, Lee, Kiho, Samuel, Melissa S., Whitworth, Kristin M., Murphy, Clifton N., Egen, Tina, Green, Jonathan A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754101/
https://ncbi.nlm.nih.gov/pubmed/23785195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00177-13
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