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The Amphipathic Helix of Influenza A Virus M2 Protein Is Required for Filamentous Bud Formation and Scission of Filamentous and Spherical Particles

Influenza virus assembles and buds at the infected-cell plasma membrane. This involves extrusion of the plasma membrane followed by scission of the bud, resulting in severing the nascent virion from its former host. The influenza virus M2 ion channel protein contains in its cytoplasmic tail a membra...

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Bibliographic Details
Main Authors: Roberts, Kari L., Leser, George P., Ma, Chunlong, Lamb, Robert A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754012/
https://ncbi.nlm.nih.gov/pubmed/23843641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01363-13
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