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Influenza Virus Hemagglutinin and Neuraminidase, but Not the Matrix Protein, Are Required for Assembly and Budding of Plasmid-Derived Virus-Like Particles

For influenza virus, we developed an efficient, noncytotoxic, plasmid-based virus-like particle (VLP) system to reflect authentic virus particles. This system was characterized biochemically by analysis of VLP protein composition, morphologically by electron microscopy, and functionally with a VLP i...

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Detalhes bibliográficos
Main Authors: Chen, Benjamin J., Leser, George P., Morita, Eiji, Lamb, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933269/
https://ncbi.nlm.nih.gov/pubmed/17475660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00361-07
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