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Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA

The bacteriophage phi29 DNA packaging motor, one of the strongest biological motors characterized to date, is geared by a packaging RNA (pRNA) ring. When assembled from three RNA fragments, its three-way junction (3WJ) motif is highly thermostable, is resistant to 8 M urea, and remains associated at...

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Detalhes bibliográficos
Main Authors: Zhang, Hui, Endrizzi, James A., Shu, Yi, Haque, Farzin, Sauter, Claude, Shlyakhtenko, Lyudmila S., Lyubchenko, Yuri, Guo, Peixuan, Chi, Young-In
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753930/
https://ncbi.nlm.nih.gov/pubmed/23884902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.037077.112
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