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Assessment and comparison of thermal stability of phosphorothioate-DNA, DNA, RNA, 2′-F RNA, and LNA in the context of Phi29 pRNA 3WJ

The question of whether RNA is more stable or unstable compared to DNA or other nucleic acids has long been a subject of extensive scrutiny and public attention. Recently, thermodynamically stable and degradation-resistant RNA motifs have been utilized in RNA nanotechnology to build desired architec...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Piao, Xijun, Wang, Hongzhi, Binzel, Daniel W., Guo, Peixuan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733572/
https://ncbi.nlm.nih.gov/pubmed/29051199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.063057.117
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