Program Specificity for Ptf1a in Pancreas versus Neural Tube Development Correlates with Distinct Collaborating Cofactors and Chromatin Accessibility

The lineage-specific basic helix-loop-helix transcription factor Ptf1a is a critical driver for development of both the pancreas and nervous system. How one transcription factor controls diverse programs of gene expression is a fundamental question in developmental biology. To uncover molecular stra...

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Main Authors: Meredith, David M., Borromeo, Mark D., Deering, Tye G., Casey, Bradford H., Savage, Trisha K., Mayer, Paul R., Hoang, Chinh, Tung, Kuang-Chi, Kumar, Manonmani, Shen, Chengcheng, Swift, Galvin H., MacDonald, Raymond J., Johnson, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753895/
https://ncbi.nlm.nih.gov/pubmed/23754747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00364-13
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