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Polyacrylamide brush layer for Hydrophilic Interaction Liquid Chromatography of intact glycoproteins

A chromatographic column of nonporous silica particles with a bonded phase of linear polyacrylamide chains is evaluated for hydrophilic interaction liquid chromatography (HILIC) of intact glycoproteins. The column is shown to retain glycoproteins significantly more strongly than non-glycoproteins. A...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Zhaorui, Wu, Zhen, Wirth, Mary J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753879/
https://ncbi.nlm.nih.gov/pubmed/23806357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2013.05.076
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