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Self-Association of the Gal4 Inhibitor Protein Gal80 Is Impaired by Gal3: Evidence for a New Mechanism in the GAL Gene Switch

The DNA-binding transcriptional activator Gal4 and its regulators Gal80 and Gal3 constitute a galactose-responsive switch for the GAL genes of Saccharomyces cerevisiae. Gal4 binds to GAL gene UAS(GAL) (upstream activation sequence in GAL gene promoter) sites as a dimer via its N-terminal domain and...

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Main Authors: Egriboz, Onur, Goswami, Sudip, Tao, Xiaorong, Dotts, Kathleen, Schaeffer, Christie, Pilauri, Vepkhia, Hopper, James E.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753875/
https://ncbi.nlm.nih.gov/pubmed/23858060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00646-12
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