The Gal3p-Gal80p-Gal4p Transcription Switch of Yeast: Gal3p Destabilizes the Gal80p-Gal4p Complex in Response to Galactose and ATP

The Gal3, Gal80, and Gal4 proteins of Saccharomyces cerevisiae comprise a signal transducer that governs the galactose-inducible Gal4p-mediated transcription activation of GAL regulon genes. In the absence of galactose, Gal80p binds to Gal4p and prohibits Gal4p from activating transcription, whereas...

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Main Authors: Sil, Alok Kumar, Alam, Samina, Xin, Ping, Ma, Ly, Morgan, Melissa, Lebo, Colleen M., Woods, Michael P., Hopper, James E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Transcriptional Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC84853/
https://ncbi.nlm.nih.gov/pubmed/10523671
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