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A Negative-Feedback Loop between the Detoxification/Antioxidant Response Factor SKN-1 and Its Repressor WDR-23 Matches Organism Needs with Environmental Conditions

Negative-feedback loops between transcription factors and repressors in responses to xenobiotics, oxidants, heat, hypoxia, DNA damage, and infection have been described. Although common, the function of feedback is largely unstudied. Here, we define a negative-feedback loop between the Caenorhabditi...

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Main Authors: Leung, Chi K., Wang, Ying, Deonarine, Andrew, Tang, Lanlan, Prasse, Stephanie, Choe, Keith P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753843/
https://ncbi.nlm.nih.gov/pubmed/23836880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00245-13
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