A Negative-Feedback Loop between the Detoxification/Antioxidant Response Factor SKN-1 and Its Repressor WDR-23 Matches Organism Needs with Environmental Conditions

Negative-feedback loops between transcription factors and repressors in responses to xenobiotics, oxidants, heat, hypoxia, DNA damage, and infection have been described. Although common, the function of feedback is largely unstudied. Here, we define a negative-feedback loop between the Caenorhabditi...

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Hauptverfasser: Leung, Chi K., Wang, Ying, Deonarine, Andrew, Tang, Lanlan, Prasse, Stephanie, Choe, Keith P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753843/
https://ncbi.nlm.nih.gov/pubmed/23836880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00245-13
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