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The hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E(−/− mice)

BACKGROUND AND PURPOSE: Atherosclerosis is associated with reduced vascular hydrogen sulfide (H(2)S) biosynthesis. GYY4137 is a novel slow-releasing H(2)S compound that may effectively mimic the time course of H(2)S release in vivo. However, it is not known whether GYY4137 affects atherosclerosis. E...

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Détails bibliographiques
Auteurs principaux: Liu, Zhen, Han, Yi, Li, Ling, Lu, Hui, Meng, Guoliang, Li, Xiaozhen, Shirhan, Mohammed, Peh, Meng Teng, Xie, Liping, Zhou, Suming, Wang, Xiaowei, Chen, Qi, Dai, Weilu, Tan, Choon-Hong, Pan, Shiyang, Moore, Philip K, Ji, Yong
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753836/
https://ncbi.nlm.nih.gov/pubmed/23713790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12246
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