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Inhibiting the DNA damage response as a therapeutic manoeuvre in cancer
The DNA damage response (DDR), consisting of an orchestrated network of proteins effecting repair and signalling to cell cycle arrest, to allow time to repair, is essential for cell viability and to prevent DNA damage being passed on to daughter cells. The DDR is dysregulated in cancer with some pat...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753833/ https://ncbi.nlm.nih.gov/pubmed/23682925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12244 |
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