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-OH No! hiPSCs misplace their 5hmCs
hiPSCs and hESCs are thought to display subtle genetic and epigenetic variability. Recently in Nature Cell Biology, Wang et al (2013) demonstrated a role for TET1 during reprogramming of human cells and showed that hiPSCs lack appropriate 5hmC marks in subtelomeric regions, contributing to epigeneti...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753777/ https://ncbi.nlm.nih.gov/pubmed/23827705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.06.007 |
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