Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR) is the leading cause of blindness in working age Americans. We demonstrated that diabetes disturbs the homeostasis of nerve growth factor (NGF) resulting in accumulation of its precursor proNGF. Increases in proNGF were positively correlated with progression...

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Detalhes bibliográficos
Main Authors: Elshaer, Sally L., Abdelsaid, Mohammed A., Al-Azayzih, Ahmad, Kumar, Parag, Matragoon, Suraporn, Nussbaum, Julian J., El-Remessy, Azza B.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753742/
https://ncbi.nlm.nih.gov/pubmed/23998130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/432659
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