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Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR) is the leading cause of blindness in working age Americans. We demonstrated that diabetes disturbs the homeostasis of nerve growth factor (NGF) resulting in accumulation of its precursor proNGF. Increases in proNGF were positively correlated with progression...

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Main Authors: Elshaer, Sally L., Abdelsaid, Mohammed A., Al-Azayzih, Ahmad, Kumar, Parag, Matragoon, Suraporn, Nussbaum, Julian J., El-Remessy, Azza B.
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753742/
https://ncbi.nlm.nih.gov/pubmed/23998130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/432659
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