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Cooperativity and interaction energy threshold effects in recognition of the −10 promoter element by bacterial RNA polymerase

RNA polymerase (RNAP) melts promoter DNA to form transcription-competent open promoter complex (RP(o)). Interaction of the RNAP σ subunit with non-template strand bases of a conserved −10 element (consensus sequence T(−12)A(−11)T(−10)A(−9)A(−8)T(−7)) is an important source of energy-driving localize...

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Autori principali: Mekler, Vladimir, Severinov, Konstantin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753650/
https://ncbi.nlm.nih.gov/pubmed/23771146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt541
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