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Binding of RNA by APOBEC3G controls deamination-independent restriction of retroviruses

APOBEC3G (A3G) is a host-encoded protein that potently restricts the infectivity of a broad range of retroviruses. This can occur by mechanisms dependent on catalytic activity, resulting in the mutagenic deamination of nascent viral cDNA, and/or by other means that are independent of its catalytic a...

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Detalhes bibliográficos
Main Authors: Bélanger, Kasandra, Savoie, Mathieu, Rosales Gerpe, María Carla, Couture, Jean-François, Langlois, Marc-André
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753645/
https://ncbi.nlm.nih.gov/pubmed/23761443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt527
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